Cephalosporin C

Cephalosporins are used to treat bacterial infections such as respiratory tract infections, skin infections and urinary tract infections. When a cephalosporin or any other antibiotic is given as a treatment, the medication should be taken for the fully prescribed time even if symptoms disappear. ==Mechanism of action==

Cephalosporin C acts by inhibiting penicillin binding proteins. == Side effects ==

These are allergic reactions to the drug and require medical attention: • itching • swelling • dizziness • rash • trouble breathing • vomiting • severe stomach cramps • bloody diarrhea • fever • weakness • fast heartbeat == Chemistry ==

Cephalosporin C has weak activity to the staphylococci infection, which was 0.1% activity. This decrease in activity was due to the replacement of the D-α-aminoadipic acid side chain with phenylacetic acid. == Biochemistry ==

Cephalosporin C is the product of a natural biosynthesis pathway that starts with penicillin N (also called adicillin). Industrial production uses a strain of the fungus Acremonium chrysogenum which has been optimised by molecular biology techniques to give a high yield of cephalosporin C. The enzymes involved are deacetoxycephalosporin-C synthase (DAOCS), deacetoxycephalosporin-C hydroxylase (DACS) and deacetylcephalosporin-C acetyltransferase (DAC-AT). ==References==