In 1509, he married Francoise de Montbel (d. ), a daughter of Jacques de Montbel, Count d'Entrémont and Jeanne de Saint-Maur. Together, they had several children, including: •
Philip de Lannoy, 2nd Prince of Sulmona (1514–1553), who married
Isabella Colonna, widow of
Louis "Rodomonte" Gonzaga, in 1534. • Ferdinand de Lannoy, Count
de La Roche (1520–1579), who married Marguerite Perrenot de Granvelle, a daughter of
Nicolas Perrenot de Granvelle (a close adviser to
Emperor Charles V). • Georges de Lannoy, 2nd Duke of Boiano, who married Julia Diaz Carlon, a daughter of Antonio Diaz Carlon, 3rd Count of
Alife, and Cornelia
Piccolomini. • Clemente de Lannoy, Baron of Prata, who married Ippolita Branai Castriota Scanderbegh, a daughter of Ferrante Castriota, Marquess of Città Sant'Angelo and Camilla Branai Castriota Scanderbegh. He died of a sudden illness in
Naples on 23 September 1527. He was succeeded by his son
Philip. ==References==