Charles Middleton may refer to:Charles Middleton, 2nd Earl of Middleton (1649/50–1719), Scottish and English politician Charles Middleton, 1st Baron Barham (1726–1813), British aristocrat, First Lord of the Admiralty Charles Middleton (cricketer) (1868–1938), English cricketer Charles Middleton (actor) (1874–1949), known for his portrayal of Ming the Merciless Charlie Middleton (footballer) (1910–1984), English footballer Charles R. Middleton, president of Roosevelt University from 2002 to 2015 Charles G. Middleton, chief of the Savannah Fire Department until 2018