In 1942, Simkins lost her position with the Tuberculosis Association, partly due to her increasing involvement with the
NAACP (National Association for the Advancement of Colored People). In 1939, when the South Carolina NAACP was formed, Simkins was already a member of the executive board of the local Columbia NAACP branch and the chair of its program committee. Simkins became one of the founders of the state conference, elected to the first executive board, and the first chair of the state programs committee. In 1941, she was elected Secretary of the state conference, the only woman to serve as an officer. During her tenure as Secretary (1941–57), her work helped the state move towards racial equality. From 1943 to 1945, she was instrumental in gaining teacher approval and support for teacher equalization lawsuits in
Sumter, South Carolina, and Columbia, South Carolina. Perhaps her most significant work took place in 1950 with the South Carolina federal court case of
Briggs v. Elliott. Simkins was involved in
Republican Party politics until 1952, when she switched to the
Democratic Party and voted for
Adlai Stevenson. Working with the Reverend
Joseph DeLaine, president of the
Clarendon County, South Carolina NAACP, she helped write the declaration for the school lawsuit that asked for the equalization of Clarendon County black and white schools. The Clarendon County case was eventually reworked to become one of several individual cases set up to directly challenge the "separate but equal" doctrine in the Supreme Court of the United States case of
Brown v. Board of Education in
Topeka in 1954. Because her activism was at times controversial, her life and home became targets of violence. An unknown person shot at her house during the time she was active with the NAACP. In the late 1950s, many began to accuse Simkins of being a communist. Some of her friends were members of the American Communist Party, and she was accused of subversive activities by the
Federal Bureau of Investigation and the
House Un-American Activities Committee. Furthermore, accusations against civil rights activists for being communists intensified after the
Brown decision was passed down. In 1957, Simkins was not nominated as a candidate for secretary by the Nominations Committee of the South Carolina NAACP. It was the first time in sixteen years that she did not get nominated. Some NAACP officials have suggested that her associations with communists and supposedly subversive groups were the cause of this. She remained active for many years in the
Southern Conference Educational Fund (SCEF), a southwide interracial civil rights organization, working with
James Dombrowski and
Carl and
Anne Braden. Simkins was able to serve in leadership positions that were traditionally unavailable to women in the Civil Rights Movement. In 1981, she was honored by a coalition of civil rights groups, who established an endowment in her name to provide income for activists working for the causes of the underprivileged. Hundreds of people attended a memorial service following her death on April 5, 1992, and Judge Matthew J. Perry stated: She probably will be remembered as a woman who challenged everyone. She challenged the white political leadership of the state to do what was fair and equitable among all people and she challenged black citizens to stand up and demand their rightful place in the state and the nation. ==Death and legacy==