On 28 March 1748, she married
William Cavendish, then the
Marquess of Hartington, who later became the 4th
Duke of Devonshire and the
Prime Minister of Great Britain. The advantageous union had been arranged since childhood and was happy. The marriage helped him rise politically. They had four children:
William,
Dorothy,
Richard, and
George.
Baroness Clifford of Londesborough Charlotte inherited great wealth upon the death of her father in 1754. As the heir of her father, she succeeded to the title of Baroness Clifford of Londesborough
suo jure. Through her marriage, the Cavendish family, with the main title of
Duke of Devonshire, inherited the 3rd Earl of Burlington's estates (the title went to the Orrery Boyles). These estates included:
Burlington House,
Piccadilly,
London (now the
Royal Academy of Arts);
Chiswick House, London;
Londesborough Hall, Yorkshire;
Bolton Abbey, Yorkshire;
Lismore Castle,
County Waterford, Ireland. Charlotte was her father's sole remaining heir. The Marchioness of Hartington died on 8 December 1754 at
Uppingham,
Rutland from
smallpox. The next year her husband William succeeded his father as Duke of Devonshire.
Issue Charlotte and her husband William had four children: •
William Cavendish, 5th Duke of Devonshire (14 December 1748 – 29 July 1811) •
Lady Dorothy Cavendish (27 August 1750 – 3 June 1794), married
William Cavendish-Bentinck, 3rd Duke of Portland. •
Lord Richard Cavendish (19 June 1752 – 7 September 1781) •
George Augustus Henry Cavendish, 1st Earl of Burlington (31 March 1754 – 4 May 1834) ==Ancestors==