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Cherry eye

Cherry eye is a disorder of the nictitating membrane (NM), also called the third eyelid, present in the eyes of dogs and cats. Cherry eye is most often seen in young dogs under the age of two. Common misnomers include adenitis, hyperplasia, adenoma of the gland of the third eyelid; however, cherry eye is not caused by hyperplasia, neoplasia, or primary inflammation. In many species, the third eyelid plays an essential role in vision by supplying oxygen and nutrients to the eye via tear production. Normally, the gland can turn inside-out without detachment. Cherry eye results from a defect in the retinaculum which is responsible for anchoring the gland to the periorbita. This defect causes the gland to prolapse and protrude from the eye as a red fleshy mass. Problems arise as sensitive tissue dries out and is subjected to external trauma Exposure of the tissue often results in secondary inflammation, swelling, or infection. If left untreated, this condition can lead to dry eye syndrome and other complications.

Description
Cherry eye is most common in young dogs, especially breeds such as Beagle, Cavalier King Charles Spaniel, English Bulldog, Lhasa Apso, Shih Tzu, West Highland White Terrier, Pug, Bloodhound, American Cocker Spaniel, and Boston Terrier. A similar condition exists in dwarf lop-eared rabbits, which occurs in the harderian gland. Similar surgical treatment is necessary. Some breeds are considered to be more susceptible to its development than others, including the Bulldog, Boston Terrier, Bull Terrier, Lhasa Apso, Cocker Spaniel, St. Bernard, Shar-pei, Shih Tzu and Poodle The NM contains many glands which merge and appear as a single gland. Typically, glands secrete tears for lubrication of the cornea. Lack of anchoring allows the gland to flip up, causing the gland to prolapse. Symptoms include a visible fleshy mass, abnormal tear production, and a discharge or drainage from the eye. Cherry eye is typically diagnosed by examination of the conjunctiva and nictitating membrane. The most obvious symptom of cherry eye is a round fleshy mass in the medial canthus of the eye, similar in appearance to the fruit it is named for. This mass may be unilateral or bilateral. Both eyes may develop cherry eye at different times in the animal's life. Other symptoms of cherry eye include drainage from the eye and abnormal tear production. Initially, cherry eye results in overproduction of tears, but eventually changes to unsubstantial tear production. ==Treatment==
Treatment
Non-surgical Cherry eye, if caught early, can be resolved with a downward diagonal-toward-snout closed-eye massage of the affected eye or occasionally self-corrects alone or with antibiotics and steroids. KCS is a chronic degenerative conjunctivitis that can lead to impaired vision and blindness. Surgery types are broken into two groups: anchoring procedures and pocket/envelope procedures. At least 8 surgical techniques currently exist. In anchoring procedures, the prolapsed gland must be sutured to the periorbital fascia, the sclera, or the base of the third eyelid. In contrast, pocket procedures involve suturing healthy tissue around the prolapsed to enclose and secure it. Each of these techniques may be performed with an anterior or superior approach, depending on which direction of suturing will cause the least complications to the eye. Anchoring method Originally, the anchoring method involved suturing the gland to the globe. This method was superseded over time due to the risky and difficult nature of the surgery, along with a high rate of recurrence. Anchoring approaches from posterior may disrupt normal fluid excretion. Subsequently, an anterior approach was introduced. Disadvantages of anchoring techniques include restricted mobility of third eyelid, which is essential in the functions of fluid distribution and self-cleaning. New procedures are currently being explored to allow tacking of the NM without restricting movement of the third eyelid. Few studies compare results of surgeries, therefore choosing a procedure is a matter of preference. Envelope/pocket method The envelope method, often called the pocket technique, requires suturing of tissue around the prolapse, encasing it in a layer of conjunctiva. Pocket techniques are easiest for doctors to learn. Pocket methods also have anterior and posterior versions. Posterior suturing techniques are the most commonly used because they cause the least complications, with no alterations in tear production. Surgery should only be attempted by experienced surgeons. Inappropriate surgical techniques can result in many complications including cysts on the eye. ==Prognosis==
Prognosis
Without treatment Previously, treatment was thought optional until the role of NM was fully understood. If exposed for extended periods of time, the gland is at risk for trauma, secondary infection, and reduced tear production. Many complications can arise if left untreated: early closed-eye massage manipulation is recommended to prevent inflammation . Post treatment Postoperative treatment includes antibiotic eye ointment three times daily for two weeks. It is possible to have a relapse of the gland after surgery and require multiple surgeries. With treatment, it is possible for animals to live a normal life. ==See also==
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