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Serpiginous choroiditis

Serpiginous choroiditis, also known as geographic helicoid peripapillary choroidopathy (GHPC), is a rare, chronic, progressive, and recurrent bilateral inflammatory disease involving the retinal pigment epithelium (RPE), the choriocapillaries, and the choroid. It affects adult men and women equally in the second to seventh decades of life.

Presentation
Serpiginous choroiditis is characterized acutely by irregular, gray-white or cream-yellow subretinal infiltrates at the level of the choriocapillaries and the RPE. Based on clinical presentation, it can be classified into peripapillary, macular, and ampiginous types. The clinical course, regardless of the presentation, is progressive, with multiple recurrences leading to potentially significant visual loss. The distinction between these two conditions is important as the latter responds to anti tuberculosis treatment while the former does not. Choroidal neovascularization (CNV) is the most common complication associated with Serpiginous choroiditis. ==Treatment==
Treatment
It is crucial to initiate rapid and effective treatment to preserve retinal function. High-doses of intravenous pulse steroids can help preserve retinal function. Immunosuppressive agents can help lengthen periods of disease inactivity and reduce the risk of potential side effects associated with high-dose steroids. ==Sources==
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