Modestou first professional job was in the ensemble of
We Will Rock You in 2010, where she also covered the role of Killer Queen. In 2014, Modestou was part of the
Southwark Playhouse cast of the UK premiere of the musical
In the Heights in the role of Nina. The cast included
David Bedella as Kevin, Sam Mackay as Usnavi,
Emma Kingston as Vanessa,
Victoria Hamilton-Barritt as Daniela, Sara Naudi as Carla and
Eve Polycarpou as Abuela. The show then transferred to the
Charing Cross Theatre with a new cast. Modestou then joined the cast of
Urinetown in 2014, for its run at the
Apollo Theatre.
Jenna Russell played Penelope Pennywise. The show moved after a successful run at the
St. James Theatre. In 2015 she joined the UK tour cast of
Shrek the Musical as part of the ensemble. Following this it was part of the ensemble of the 20th anniversary production of
RENT first a
The Other Palace and then embarking on a UK tour. In 2017, she joined the cast of
Six for their performances at the
Arts Theatre in
London. She worked extensively with
Lucy Moss and
Toby Marlow, the creators of the musical, and despite the fact that the original 2017 performances weren't in costume, Modestou went on to take part in the studio album, singing the role of
Anne Boleyn (whom she originated), which was recorded and later released in 2018. After the release of the studio album, Modestou left the cast of
Six and she was replaced with
Millie O'Connell in the
West End productions and later
Andrea Macasaet in the
Broadway productions. In 2018 Modestou was part of the
Regent's Park Open Air Theatre production of
The Little Shop of Horrors as Ronnette. Other cast member included: fellow
Six castmate Renée Lamb and
Vicky Vox as Audrey II. In 2021 Modestou returned to the Open Air Theatre for their production of Carousel, in the role of Claire Pipperidge, directed by Timothy Sheader, who was involved in several Open Air productions through the years. Following the summer season Modestou was announced as part of the cast of the touring production of
Fantastically Great Women Who Changed the World, show inspired by
Kate Pankhurst's picture book. Modestou played Gertrude Ederle/Jane Austen/Mary Anning/Anne Frank and was joined by Renée Lamb and
Frances Mayli McCann. == Theatre credits ==