Christopher Leigh Williams is an American medical physicist and NASA astronaut. Selected in 2021, Williams is currently on his first mission aboard Soyuz MS-28 in November 2025, serving as a flight engineer and member of Expedition 73/74 on the International Space Station. He is expected to spend approximately eight months aboard the station, contributing to various scientific investigations and technology demonstrations. Before joining NASA, Williams worked at Harvard Medical School, Brigham and Women's Hospital, and the Dana–Farber Cancer Institute, where he led efforts in MRI-guided radiation therapy for cancer treatment. He holds a Ph.D. in physics from the Massachusetts Institute of Technology and is board-certified in medical physics.