The parish was founded in 1876 with the Rev. Martin J. Brophy as the first pastor. The congregation first met in the former Plymouth Baptist Church at 487 West 51st Street. Vicar-General Mooney, pastor of the church in the 1890s, was a strong proponent of the parochial school system, as opposed to secular public schools. During a sermon at the dedication to the now closed and demolished
St. Rose of Lima Parish School, he "urged his hearers to send their children to the parochial schools, where, he said, the religious instruction they would receive was far more important than the secular instruction they could receive in the public schools." ==Buildings==