De Angelis was born in Anagni on 5 April 1675 as the fourth child of six children. Her parents, Alessandro De Angelis and Elisabetta Spinelli, came from noble families. In her childhood, she suffered a fragile health and this was also due to her mother's neglect. Her spiritual father,
Giovanni Marangoni carried out De Angelis' wish of completing the construction of the pious schools. ==References==