After earning her PhD, de Rham went to Montreal to join the physics department at
McGill University. She moved to
McMaster University in Hamilton and the
Perimeter Institute for Theoretical Physics in Waterloo, Ontario, in 2006, where she worked in a joint postdoctoral position in cosmology. In 2010, she joined the
University of Geneva as an assistant professor. She moved to
Case Western Reserve University in Cleveland, Ohio, in 2011 and became an associate professor there in 2016. She joined
Imperial College London in 2016. That year, she was awarded a £100,000 Wolfson Merit Award from the
Royal Society. Her research is in the area of
theoretical cosmology, and she explores gravitational models that could explain the accelerated expansion of the universe. De Rham is recognised as a researcher at the forefront of the development of theories of
massive gravity, where the particle carrier of the gravitational force, the
graviton, may be massive. In 2010, she constructed a nonlinear theory of a massive graviton, which is theoretically consistent and
ghost-free. That formulation of massive gravity is now known as "de Rham-Gabadadze-Tolley (dRGT) theory", owing to its discovery by de Rham,
Gregory Gabadadze, and Andrew J. Tolley. De Rham was interviewed by
Morgan Freeman in season 8 of
Through the Wormhole. ==Publications==