Clay divided the Ashland estate among three sons. After his father's death, son
James Brown Clay owned and occupied Ashland and a surrounding tract of about . James Clay had the house razed in 1854, and rebuilding was completed by 1857. Local architect
Thomas Lewinski designed the new structure, which used features of the original house: the footprint and foundation, floorplan, and massing, but Lewinski modernized the house stylistically. With many
Italianate features, the resulting
mansion is a mix of
Federal architecture and
Italianate details. Inside, James Clay employed
Greek Revival features and decorated the home lavishly (see:
Victorian decorative arts) with imported furnishings purchased in
New York City. James Clay rebuilt the house and his family lived there until his death in 1864. His widow Susan Jacob Clay sold the estate in 1866.
Kentucky University purchased Ashland and used it as part of its campus. University founder and regent
John Bryan Bowman occupied the mansion. The Agricultural and Mechanical College (Kentucky A & M) sat on Clay's former farm. During the
Kentucky University period, Regent John Bowman used part of the mansion to house and display the University Natural History Museum. Kentucky University split into what became
Transylvania University and the
University of Kentucky, and sold Ashland in 1882. Henry Clay's granddaughter Anne Clay McDowell and her husband
Henry Clay McDowell purchased the estate (consisting of about and outbuildings) and moved in with their children in 1883. They remodeled and modernized the house, updating it with gas lighting (later, electricity),
indoor plumbing, and telephone service. Their eldest daughter Nannette McDowell Bullock continued to occupy Ashland until her death in 1948. She founded the Henry Clay Memorial Foundation, which purchased and preserved Ashland. The historic house museum opened to the public in 1950. ==Plantation name==