For centuries the land on which Clayesmore now stands was held by
Shaftesbury Abbey. After the
dissolution it passed to the Bowyer Bower family. Their family home was built in 1796 roughly on the site of the existing main building. In 1876 the last member of the Bowyer Bower family, Captain T Bowyer Bower, sold the village and estate to
George Glyn, 2nd Baron Wolverton. The Baron demolished the house, laid out the Iwerne estate afresh and commissioned
Alfred Waterhouse to design the present building (now Wolverton House) which was completed in 1878. In 1904 the
4th Baron Wolverton put the whole estate up for sale. This was bought in 1908 by
James Ismay whose father,
Thomas Henry Ismay, had founded the
White Star Line shipping company. On Ismay's death in January 1930 the estate was put up for sale in a number of separate lots. Clayesmore School bought the main manor house and the in which it stands, and the school moved in during 1933. For over 60 years, starting in 1940, the school's buildings were used during school holidays as the location for the
Evangelical Christian Iwerne camps. In 1974, Clayesmore merged with Charlton Marshall School, which later became Clayesmore Prep School. The school became co-educational in 1975. Clayesmore School officially joined the Inspired Learning Group on September 1, 2025. This is a significant change in the school's 130-year history. == Iwerne camps ==