Early career Born in
Botucatu,
São Paulo, Clayson made his senior debuts for
União São João in 2012, aged only 16. After scoring one goal in three appearances, he was loaned to
Grêmio, returning to youth setup.
Ituano On 18 February 2013 Clayson joined
Ituano, making his debut for the club on 24 March, coming on as a second-half
substitute in a 1–2 home loss against
Oeste for the
Campeonato Paulista championship. He scored his first professional goal on 15 March 2015, netting his side's only in a 1–2 loss at
Grêmio Osasco Audax.
Ponte Preta On 28 August 2015, Clayson signed for
Série A club
Ponte Preta, on loan until the end of the year. He made his debut in the category on 2 September, replacing
Biro-Biro in a 1–2 home loss against
Cruzeiro. On 18 November 2015, Ponte bought Clayson outright, with his new five-year contract being effective the following January. He established himself as a starter for the club during
the season, and scored his first top tier goal on 3 June 2016 by netting the second in a 2–1 away win against
América Mineiro.
Corinthians In June 2017, Clayson joined Corinthians, where he was part of the squad that won the
2017 Campeonato Brasileiro Série A.
Bahia In 2020 he joined Bahia. He was loaned out to Cuiaba for the 2021 season.
Al-Faisaly On 30 January 2022, Clayson joined Saudi Arabian club
Al-Faisaly.
V-Varen Nagasaki On 11 July 2022, Clayson joined Japanese club
V-Varen Nagasaki.
Cuiaba In June 2023 Cuiaba bought Clayson. On 6 August 2023, he scored in a 3–0 victory against
Flamengo. ==Career statistics==