Clayton School for Boys, established as George W. Clayton Trust & College and also known as Clayton College, was established to house and educate boys whose fathers had died and whose mothers could not provide for them. It was established in 1911 by the City of Denver from a bequest by George Washington Clayton (1833–1899), a merchant and real estate investor. The campus was designed by Biscoe & Hewitt in the Italian Renaissance Revival style and includes sandstone masonry.