MarketClostridium acetobutylicum
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Clostridium acetobutylicum

Clostridium acetobutylicum, ATCC 824, is a commercially valuable bacterium sometimes called the Weizmann organism, after Jewish Russian-born biochemist Chaim Weizmann. A senior lecturer at the University of Manchester, England, he used them in 1916 as a bio-chemical tool to produce at the same time, jointly, acetone, ethanol, and n-butanol from starch. The method has been described since as the ABE process (acetone-butanol-ethanol fermentation process), yielding 3 parts of acetone, 6 of n-butanol, and 1 of ethanol. Acetone was used in the important wartime task of casting cordite. The alcohols were used to produce vehicle fuels and synthetic rubber.

In genetic engineering
In 2008, a strain of Escherichia coli was genetically engineered to synthesize butanol; the genes were derived from Clostridium acetobutylicum. In 2013, the first microbial production of short-chain alkanes was reported - which is a considerable step toward the production of gasoline. One of the crucial enzymes - a fatty acyl-CoA reductase - came from Clostridium acetobutylicum. ==See also==
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