Procoagulant platelets are a functional subgroup of
platelets with distinct properties in physiological
hemostasis. Following strong activation, procoagulant platelets express
phosphatidylserine on their surface and become highly efficient in sustaining
thrombin generation and parallelly gain pro-haemostatic function by retaining
α-granule proteins on their membranes. While a low level of procoagulant platelets is associated with impaired platelet function and bleeding diathesis high levels have been shown to worsen thrombotic events. ==References==