Colhuehuapisuchus is an extinct genus of peirosaurid notosuchian known from the Late Cretaceous Lago Colhué Huapí Formation in Argentina. It contains a single species, Colhuehuapisuchus lunai. It is known from a single anterior end of a lower mandible. Its name comes from the formation its holotype was found, the Lago Colhué Huapí Formation along with the suffix -suchus, from Greek, which is often used as the suffix for crocodilians.