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Catherine O'Hara as Liz Larsen, a level-headed mother and high-flying business woman who has to deal with misogyny at work and a chaotic household at home. •
Eugene Levy as Joe Larsen, a well-meaning but lazy father who reviews video games for an online journal. •
Andrea Martin as Frances Wilder, Liz's highly paranoid and hypochondriac mother who doesn't approve of Joe, and regularly criticises her daughter. •
Dave Foley as Bob the Dog, a lazy and unmotivated dog who often comments to the audience on the chaos unfolding around him. •
Annick Obonsawin as Tracy Larsen, Liz and Joe's eldest daughter who likes all things girly, which concerns Liz who fears she'll become shackled to traditional gender roles. •
Charlotte Arnold as Zelda Larsen, the middle child and a tomboy who gets along well with Joe due to sharing a lot of interests with him. • Cole Caplan as Nicholas Larsen, the youngest child and Liz and Joe's only son. He often displays effeminate behaviour, much to Joe's dismay as he wants his son to be more manly. • Oscar Hsu as Gary Wong, a pizza shop owner who Liz often calls to ask for advice from. •
Ron Pardo as Cal, Liz's sexist and dishonest coworker who is more than willing to trample over Liz's career prospects to advance his own career. •
Linda Kash as Val, the vain wife of Liz's boss who looks down on Liz for her perceived lack of fashion sense, and her decision to have kids. •
Len Carlson as Additional Voices •
Greg Spottiswood as Additional Voices •
Adrian Truss as Additional Voices == Episodes ==