Ancient Roman cognomen •
Africanus Fabius Maximus, a Roman senator, the younger son of Quintus Fabius Maximus (consul 45 BC) •
Cresconius Africanus, a Latin canon lawyer, probably latter half of 7th century •
Julius Africanus, an orator in the time of Nero () •
Titus Sextius Africanus (1st century), a censor of Gaul •
Lucius Apuleius Africanus Madaurensis (), a Latin-language prose writer •
Titus Sextius Cornelius Africanus, a consul under Trajan () •
Sextus Caecilius Africanus (2nd century), a Roman legal scholar •
Scipio Africanus (disambiguation) •
Sextus Julius Africanus (), a Christian traveller and historian •
Junillus Africanus (), a Quaestor of the Sacred Palace in the court of the Byzantine Emperor Justinian I •
Constantine the African (11th century), i.e. Constantinus Africanus, a physician who lived in the 11th century.
Given name or surname •
George Africanus (1763–1834), a West African slave, later credited as Nottingham's first black entrepreneur •
Leo Africanus (1488–1554), an Andalusi diplomat and author •
Scipio Africanus (disambiguation) •
Africanus Horton (1835–1883), also known as James Beale, a writer and folklorist from Sierra Leone •
Albert Freeman Africanus King (1841–1914), American physician ==Other uses==