Introduction This section discusses venture capital activities of
healthcare providers such as
Ascension Health,
biotech firms such as
Biogen Idec, and
pharmaceutical companies such as
GlaxoSmithKline, all of which are healthcare-related companies and have internal venture capital units or wholly owned
subsidiaries focused on venture capital. The structure of corporate venture capital within the healthcare arena; the most common types of investments made; and the main reasons for which healthcare companies invest will be addressed, as well as the current trends and some predictions for the industry.
Structure By definition, the corporate venture capital field is made up of organizations whose primary activities are not investing in other firms (see above). Since that definition rules out freestanding healthcare venture capital firms such as De Novo Ventures, as well as
publicly traded firms, what remains are a limited number of organizational structure types used by healthcare corporate venture capital. The two main types are: 1) divisions within a larger healthcare company; and 2) wholly owned subsidiaries of larger healthcare companies. CVC units of both of these types often engage in
partnerships with other firms. In most cases the other firms are
limited partners and the primary company manages the fund and is the only
general partner.
Types of investments The largest segment of healthcare-related venture capital investments are made by the venture arms of firms who focus on biotechnology and pharmaceutical products, such as
Eli Lilly and Company,
GlaxoSmithKline,
Takeda Pharmaceutical Company (TCP),
Biogen Idec, and
Roche. Because the top priority of many of these venture capital units or divisions is to fund ventures that may result in scientific and technological discoveries and advancements that may benefit their parent companies, most tend to invest in companies whose products or proposed products are similar to their own. However, the
healthcare industry is seen as somewhat recession-resistant and this has encouraged some investors within the field. As such, while most major corporations with venture capital arms are keeping cash close to home, some of the first positive movement within corporate venture capital as a whole is coming from healthcare. The new venture fund recently opened by
Merck Serono and the fund just closed by Ascension Health Ventures are just a few examples of the optimism that is slowly reentering venture capital within healthcare. The latest survey on the top 75 most influential healthcare corporate venture capital divisions shows they are increasingly influential and larger than many independent VCs. Another trend that may see more action as venture capital funds continue to be scarce is an increasing number of strategic partnerships between firms that are based not on exchange of funds, but rather on exchange of technologies or process information. These types of partnerships, also known as corporate
in-kind investments, may become increasingly common as liquid funds become less available but technologies that have been developed are readily shareable. One specific example of this sort of information exchange is a partnership between a large, well-established company and a small, developing company who have complementary technologies or processes. Such 'David and Goliath' partnerships are already starting to emerge outside of the healthcare industry and will likely emerge within healthcare soon.
Sectors Investments from venture capital firms and CVC in 1998 were mostly in software and telecommunications sectors. By 2006 the biotechnology and medical devices became the sectors with the most investments from both, venture capital firms and CVC. However, there has not been significant investments in health services and have actually decreased through these periods. Biotechnology CVC's investments in biotechnology are higher than those from VC firms. However, medical devices and health services had a is not a top sector for CVC investments as it is for VC firms. Other top sectors for CVC investments are software, telecommunications, semiconductors, and media/entertainment. Top sectors for CVC investment: •
Biotechnology, •
Software, •
Telecommunications, •
Semiconductors, and •
Media/entertainment. Top sectors for VC investment: •
Software, •
Biotechnology, •
Medical devices, and •
Telecommunications.
In the life sciences Many of today's well known companies in life sciences have been backed with billions of dollars by venture capital investments. Some of these are: Boston Scientific, Amgen, Genentech, Genzyme, Gilead Sciences, Kyphon, Intuitive Surgical, and Scimed Life Systems. From the $25.5 billion in total venture capital investments, there were $7.2 billion targeted to the life sciences industry. The life sciences include sectors in biotechnology and medical devices and equipment. Venture capital investments within biotechnology accounted for $4.5 billion and within medical devices and equipment for $2.7 billion. Venture capital investments have gone toward specific disease. For example, there was venture capital support during the past 20 years of $14.9 billion in cardiovascular/heart diseases, $14.7 billion in cancer, and $4.9 billion in diabetes.
Examples Eli Lilly Corporate Business Development Eli Lilly Corporate Business Development (CBD), CVC division from
Eli Lilly and Company:
Johnson & Johnson Development Corporation JJDC is the venture capital subsidiary of
Johnson & Johnson.
Dow Venture Capital Dow Venture Capital (DVC), CVC division from
Dow Chemical, invests in start-up companies in North America, Europe and Asia. DVC is located in company headquarters in Midland, MI; in European headquarters in Zurich; and in Gotemba, Japan.
Siemens Venture Capital Siemens Venture Capital (SVC) is the corporate venture organization for
Siemens AG. Its focus is on growth segments in the energy, industry and healthcare sectors. To date, SVC has invested over 800 million euros in more than 150 startup companies and 40 venture capital funds. SVC is located in Germany (Munich), in the U.S. (Palo Alto, CA and Boston, MA), in China (Beijing), in India (Mumbai), and is active through Siemens´ regional unit in Israel.
Kaiser Permanente Ventures Kaiser Permanente Ventures (KPV) the corporate venture capital arm of
Kaiser Permanente. KPV invests in medical devices, health care services and health care information technology companies.
Geisinger Ventures Geisinger Ventures is the corporate venture arm of
Geisinger Health System. GV invests resources in healthcare technology, information technology, medical devices, medical diagnostics and therapeutics. GV utilizes funds from its balance sheet.
Ascension Health Ventures Ascension Health Ventures was established in 2001 by
Ascension Health with a commitment of $125 million to invest in expansion- to late-stage healthcare companies.
The University of Texas Horizon Fund The UT Horizon Fund (UTHF) is the strategic corporate venture arm of
The University of Texas. The UTHF's goals are to: (1) Improve commercialization of UT technologies, and (2) Improve sustainability through a positive return on investment. The Fund is evergreen where a significant portion of gains are re-invested back into the Horizon Fund for future growth. Phase I of the Fund has been capitalized at $10M through the Available University Fund of the University of Texas. The two primary programs of the fund are: • Existing Ventures Program. Many university startups have difficulty raising desired levels of funding to continue development of technologies through to the final stages of commercialization. University equity positions may become diluted with preferred rights to new investors. The UT Horizon Fund co-invests with new investors to continue university equity participation all the way through to commercialization. By doing so, UT System can increase its return on investment both in terms of delivering real products and services beneficial to society as well as to providing financial return. • New Ventures Program. The biggest bottleneck at the earliest stages of commercialization is access to entrepreneurial talent. Seasoned entrepreneurs are necessary to help facilitate effective business planning critical for growth and development and to seek regulatory approval and other activities. About UT System: • Established by the Texas Constitution in 1876, The University of Texas System consists of nine academic universities and six health institutions, including UT Austin, UT MD Anderson Cancer Center and UT Southwestern Medical Center, along with 12 other institutions. The mission of The University of Texas System is to provide high-quality educational opportunities for the enhancement of the human resources of Texas, the nation, and the world through intellectual and personal growth. System administration is based in Austin, Texas. Offices are also located in Midland, Texas (University Lands/West Texas Operations) and Washington, D.C. (Federal Relations). These offices are responsible for the central management and coordination of the academic and health institutions. • The UT System has a special responsibility for managing the Permanent University Fund (PUF), the Available University Fund (AUF), other endowments, managing university lands, carrying out the Board of Regents' policies, collaborating with the Board of Regents on strategic planning, and serving as consultants to the institutions on issues ranging from academic programs to fund raising. In addition, the System provides a wide range of centralized, cost-effective, and value-added services on behalf of the UT institutions and the public.
Investment criteria by provider (Ascension Health example) Opportunities are evaluated for potential clinical, operational and financial benefits to our limited partner health systems in addition to the financial return to the venture fund. Diversification is also a consideration; AHV seeks to balance the portfolio across sectors and stages to mitigate investment risk. Every opportunity is evaluated against the following criteria: •
Industry - Healthcare segments including medical devices, medical and information technology and services. AHV has also selectively invested in other healthcare venture funds. •
Investment Size - Approximately $5 million per round; up to $10 million per company. •
Company Stage - Expansion- to late-stage within three to five years of a potential liquidating event. •
Adoption Potential - Sustainable competitive advantage with compelling benefit sufficient to influence market adoption. •
Management Team - Established team with demonstrated relevant experience, depth and capability to build the business to scale and attract customers. •
Other - AHV typically requests a Board observer seat for each portfolio company. ==In information and communication technology companies==