2018 The
Denver Broncos selected Sutton in the second round (40th overall) of the
2018 NFL draft. He was the third wide receiver selected that year. Sutton made his NFL debut with two receptions for 45 yards in the Broncos' season-opening 27–24 victory over the
Seattle Seahawks. In Week 5, against the
New York Jets, he scored his first professional touchdown. He finished his rookie season with 42 receptions for 704 yards and four touchdowns.
2019 In Week 1 against the
Oakland Raiders on
Monday Night Football, Sutton caught seven passes for 120 yards in the 24–16 loss. In Week 4 against the
Jacksonville Jaguars, Sutton caught six passes for 62 yards and two touchdowns in the 26–24 loss. In Week 5 against the
Los Angeles Chargers, Sutton caught four passes for 92 yards, including a 70-yard receiving touchdown, as the Broncos won their first game of the season by a score of 20–13. In Week 11 against the
Minnesota Vikings, Sutton caught five passes for 113 yards in the 27–23 loss In Week 13 against the Chargers, Sutton caught four passes for 74 yards, and rookie quarterback
Drew Lock's first two touchdown passes in the NFL, during the 23–20 victory. Overall, in the 2019 season, Sutton recorded 72 receptions for 1,112 receiving yards and six receiving touchdowns. On January 15, Sutton was moved into the Pro Bowl roster as an alternate, replacing the injured
DeAndre Hopkins, who opted to not play in the game due to a rib injury suffered in a Divisional Round playoff game versus the
Kansas City Chiefs. It was Sutton's first Pro Bowl selection, and with the selection, Sutton became the fastest Broncos wide receiver to earn a Pro Bowl nod, accomplishing it in just his second season in the NFL, breaking
Demaryius Thomas's record.
2020 After missing Week 1 with a shoulder injury, Sutton made his 2020 debut the following week against the
Pittsburgh Steelers. During the game, Sutton caught three passes for 66 yards before exiting the game with a knee injury. The next day, an MRI confirmed that Sutton suffered a torn ACL and he was placed on season-ending injured reserve on September 22, 2020.
2021 In Week 2, against the Jaguars, he had nine receptions for 159 receiving yards in the 23–13 victory. In Week 5, against the Steelers, he had seven receptions for 12 receiving yards and one receiving touchdown in the 27–19 loss. On November 22, 2021, Sutton signed a four-year $60.8 million contract extension with the Broncos through the 2025 season. Sutton finished the season with 58 receptions for 776 yards and two touchdowns.
2022 In Week 2, against the
Houston Texans, Sutton had seven receptions for 122 receiving yards in the 16–9 victory. In the 2022 season, he played in 15 games, making 64 receptions for 829 receiving yards with two receiving touchdowns.
2023 In the 2023 season, Sutton appeared in and started 14 games. He finished with 59 receptions for 772 yards and ten touchdowns. He had five consecutive games with a touchdown from Week 6 to Week 11. In Week 10 against the
Buffalo Bills, Sutton caught a touchdown pass from
Russell Wilson at the very edge of the end zone, barely tapping both of his feet in bounds. The catch was statistically the most improbable completion of the Next Gen Stats era, with only a 3.2% probability of succeeding.
2024 In Week 9, against the Baltimore Ravens, Sutton had seven receptions for 122 yards in addition to a passing touchdown thrown to
Bo Nix on a trick play. In Week 12, against the Las Vegas Raiders, he had two receiving touchdowns in the 29–19 win. He finished the 2024 season with 81 receptions for 1,081 yards and eight touchdowns helping the Broncos make the playoffs for the first time since
2015.
2025 On July 28, 2025, Sutton signed a four-year, $92 million ($41 million guaranteed) contract extension with the Broncos. He had 74 receptions for 1,017 yards and seven touchdowns in the 2025 season. He scored a receiving touchdown, which was the first of his postseason career, on Denver's lone score in the AFC Championship loss to the Patriots. ==Career statistics==