Cutaneous larva migrans

The infection causes a red, intensely pruritic (itchy) eruption and may look like twirling lesions. However the severity of the symptoms usually causes those infected to seek medical treatment before spontaneous resolution occurs. After proper treatment, migration of the larvae within the skin is halted and relief of the associated itching can occur in less than 48 hours (reported for thiabendazole). ==Cause==

Hookworm eggs are shed in infected dog (or other animal) feces and are transferred to the ground and to beach sand, where they develop over a period of 1–2 weeks into an infectious larval form (filariform larvae). The filariform larvae can burrow through intact skin which comes into contact with soil or sand that is contaminated with feces. Although they are able to infect the deeper tissues of other animals (through to the lungs and then the intestinal tract), humans are incidental hosts and the larvae are only able to penetrate the epidermis of the skin. ==Diagnosis==

Observing the lesions with the naked eye is sufficient to make a clinical diagnosis. Finding the larvae is difficult due to their small size and identifying the species to which they belong is more complicated. Therefore, careful observation of the serpiginous lesions, which progressively increase in length, as well as a history of contact with sandy soil contaminated with dog or cat feces, mainly on beaches, is considered sufficient for a correct diagnosis. == Treatment ==

CLM can be treated in a number of different ways: • Systemic (oral) agents include albendazole (trade name Albenza) and ivermectin • Another agent which can be applied either topically or taken by mouth is thiabendazole an anti-helminthic. • Topical freezing agents including ethylene chloride or liquid nitrogen, applied locally, can freeze and kill the larvae, but this method has a high failure rate because the larvae are usually located away from the site of the visible skin trails. Additionally this is a painful method which can cause blistering and/or ulceration of the skin and is therefore not recommended. • To relieve some of the itch, Benadryl or anti-itch creams such as hydrocortisone or calamine lotion can help. • Wearing shoes in areas where these parasites are known to be endemic offers protection from infection. In general avoiding exposure of skin to contaminated soil or sand offers the best protection. In some areas dogs have been prohibited from beaches in an attempt to control human infection. == See also ==