Originally the territory was occupied by the
Opatas and the
Pimas Altas. In 1647 the
Jesuit missionary Marcos del Río founded the first Spanish settlement with the category of mission and gave it the name of
Los Santos Reyes de Cucurpe. In 1859 it was given the title of "Villa" and in 1932 it became a municipality. In 1691, the Moravian Jesuit
Adam Gilg and the Carniolan Jesuit founded the mission of St. Thaddeus in Cucurpe, but it was destroyed in the same year by the
Seris. This town was once the considered the "Rim of Christendom" and it was from here that Father
Eusebio Kino rode out to do his now historic work in the area then known as the
Pimería Alta. He rode out on 14 March 1687, 24 years and one day before his death on 15 March 1711. ==Geography==