Four genes required for curdlan production have been identified in "
A. fabrum" ATCC 31749, which produces curdlan in extraordinary amounts, and the closely related
A. tumefaciens. A putative
operon contains crdS (Q9X2V0, family GT2, ), encoding β-(1,3)-glucan synthase catalytic subunit, flanked by two additional genes. A separate locus contains a putative regulatory gene, . A membrane-bound phosphatidylserine synthase, encoded by , is also necessary for maximal production of curdlan of high molecular mass. Nitrogen starvation upregulates the curdlan operon and increases the rate of curdlan synthesis. == Applications ==