Lowe began modelling at the age of two, and did some photoshoots when she was 12 and 14 years old. At 15, she was approached by a talent scout in
Camden Town and she signed with Select, a London modelling agency. In February 2006, Lowe was featured in
Vogue Italia, shot by New York photographer
Steven Klein, who also shot her in March 2007 for a
W magazine pictorial called "Xurbia". In September 2006, Lowe modelled for the
Urban Outfitters catalogue, appeared in
French Connection printed advertisements and was profiled in British ''
Harper's Bazaar. She was featured in an editorial in Jane
magazine alongside fellow model Lydia Hearst-Shaw in March 2007, appeared in Vogue Italia
for the second time in May and, in August, posed nude on the cover of i-D'' magazine with her then-partner, Will Cameron of the band
Blondelle, photographed by
Terry Richardson. On the runway, Lowe was selected by
Karl Lagerfeld to model for
Chanel, and has appeared on catwalks in New York,
Milan and London for
Topshop and designers such as PPQ,
Nanette Lepore, Sue Stemp,
Charlotte Ronson,
Henry Holland, and
Vivienne Westwood. She has modelled for
Agent Provocateur lingere for the past three years, and has been used by
Burberry,
Converse shoes,
Dr. Martens, Hooch,
Wheels and Doll Baby,
Ben Sherman,
Frost French, Hari,
Karen Millen,
Diesel SpA and
Whistles, as well as for her mother's recent collection of
lace dresses. Of the Whistles campaign, Lowe said, "[It] was a favourite shoot of mine. ... Modelling is a cool outlet for me to express myself, and fashion has always fascinated me. I love that fashion crosses into my other passions – music and art." Lowe's magazine work includes editorials and covers of publications such as
Tatler,
Elle,
GQ,
Vogue,
Paradis,
Marie Claire,
Interview,
Jalouse,
Teen Vogue,
Dirty Glam,
Grazia,
InStyle,
Nylon, and
The Sunday Times Style amongst many others. She has recently appeared in campaigns for
Marc by Marc Jacobs,
Pringle of Scotland,
DKNY,
Louis Vuitton,
Mango, and
Esprit. Lowe has some experience in other media, including being the focus of the
BBC Two eight-part
fly on the wall documentary series
Class of 2008, co-hosting
Glamour's
Best Dressed 2008 with
Peaches Geldof for
Fiver, and a brief contribution to a blog for
Elle UK online. Lowe has worked as a DJ, appeared in the music videos "
NYC Beat" by
Armand Van Helden and "Bloodthirsty Bastards" by
Dirty Pretty Things, and hosted events for
Tommy Hilfiger and
Dolce and Gabbana. 2009 also saw Lowe feature in
The First Days of Spring,
Noah and the Whale's film accompaniment to their second album. She was chosen to be in the 2010
Pirelli Calendar photographed by Terry Richardson in
Bahia, Brazil. Throughout May 2010 Lowe documented her daily fashion and style choices for Vogue.co.uk's "Today I'm Wearing" feature. In August 2010, Lowe became the face of the newly relaunched sixties label Biba. She is also the face of Stephen Webster's 2011 jewellery campaign. In 2011, Lowe went topless for
Esquire and nude for
Playboy. Also in 2011, she was featured in the music video for
Miles Kane's "
Come Closer". In October 2014, Lowe appeared in a comedy sketch with
Jimmy Carr for Channel 4's
The Feeling Nuts Comedy Night raising awareness of testicular cancer. In the sketch Carr lures Lowe to a hotel suite to check his testicles. The sketch also features
Jamie Cullum,
Lance Armstrong and
Rylan Clarke. She was number 89 on
FHM 100 Sexiest of 2015. She also had a small part in the action film
Pressure. On 17 August 2016, Lowe was announced as a contestant for
series 14 of
Strictly Come Dancing. She was partnered up with
Aljaž Škorjanec and left in week eight. Lowe started a podcast, ''Femme: It's All About Being A Woman'' and in 2019 worked with artist Jemima Sara on a related clothing line. ==Personal life==