Dame Diop started his career at
Touré Kunda. He signed with the Russian club
FC Khimki, but failed to make a league appearance before going on loan to
FC Shirak from Armenia. He joined FC Shirak permanently in 2013. On 1 August 2014, he signed a two-year contract with Czech Republic's
SK Slavia Prague. On 10 February 2016, Diop signed a two-year contract with
FC Fastav Zlín. On 22 December 2017, he signed a long-term contract with
FC Baník Ostrava. On 7 September 2022, Diop signed for
Armenian Premier League club
Pyunik. On 17 January 2023, Pyunik announced that Diop had left the club. ==International career==