At the end of
World War II, the Catholic Diocese of Honolulu saw the need for a second Catholic school on Oahu. The new school was named after Saint
Damien de Veuster, who devoted his life to caring for
Hansen's Disease patients on Molokai during the 19th century. The Congregation of Christian Brothers, parents and students volunteered to turn the land - which included of
taro patches and a good deal of uneven swampland - into a school campus because the company that started construction on Damien went bankrupt. Damien became coeducational beginning from the 2012–13 school year. On April 13, 2023, Damien Memorial School joined with their sister school,
Damien High School of La Verne, California, for the first time and planned events to hold between the two schools. In the beginning week of September 2023, Damien High School visited Damien Memorial for the second time, joining together for their first joined liturgy and football match held in the nearby Farrington High School. == Athletics ==