Mendelson began his career in health policy working for Professor William B. Schwartz at Tufts University, and co-authored a range of articles during that time. He next served as senior vice president of The Lewin Group and director of its Medical Technology Practice. Before founding Avalere, Mendelson served as associate director for health at the White House Office of Management and Budget during the
Clinton administration. In this position, he was responsible for preparing the president’s health budget in consultation with other White House offices, managing the appropriations process with members of Congress and their staffs and overseeing a range of management and budget issues in the
U.S. Department of Health and Human Services, the
United States Department of Veterans Affairs, and the Office of Personnel Management. On leaving the White House in 2000, Mendelson founded The Health Strategies Consultancy, renamed Avalere Health in 2005. The company provides advisory services, research, and data products to a range of commercial and non-profit customers with interests in healthcare, providing oft-cited studies on Medicare,
Medicaid, the
340B Drug Pricing Program, and the
health insurance marketplace. Mendelson served as CEO of Avalere until 2015 when he sold the firm to Inovalon Holdings to focus the efforts of the group on deployment of platforms to improve quality. In 2021, Mendelson was named CEO of Morgan Health, a subsidiary of JPMorgan Chase, focusing on investments in innovation in employer-sponsored health care. ==Board memberships==