The Daniel Boone Home is a historic site in Defiance, Missouri, United States. The house was built by Daniel Boone's youngest son Nathan Boone, who lived there with his family until they moved further south in 1837. The Boones had moved there from Kentucky in late 1799. Nathan later said, "In the summer of 1800, I erected a good substantial log house, and several years after that I replaced it with a commodious stone building. My father, Daniel Boone, built himself a shop and had a set of tools, and when at home he would make and repair traps and guns. In fact he did all the needed smith work for the family and sometimes for neighbors to oblige them. But after a few years he disposed of his tools." Daniel and his wife Rebecca lived primarily with their son Nathan from at least 1804 to 1813, and then for much of the time from late 1816 to his death in 1820.