Dykhuizen has published over 100 reviewed articles and book chapters with over 10,000 citations. He plans to publish a book with Tony Dean called “Experimental Evolution: the making of a field”, at the end of 2025. He was the editor in chief of the
Quarterly Review of Biology from 2010 to 2021. Examples of Dykhuizen's most notable research accomplishments include using chemostats to study natural selection; testing the energy conservation theory of Lwoff using mutations of the genes used to synthesis tryptophan; showing lateral gene transfer happens between strains of Escherichia coli; estimating that there are millions of species of bacteria; developing the metabolic flux theory of fitness with Tony Dean and Dan Hartl; (7) showing selection against wasteful synthesis of proteins depended upon use of process rather than resource; showing that the Eastern Coyote is a mixture of Western Coyote, wolf and dog; and discussing problems in public health. ==Awards and honors==