Slepian is a surname. Notable people with the surname include:Barnett Slepian (1946–1998), American physician and OB/GYN who was shot and killed in his home by an anti-abortion activist, James Charles Kopp Dan Slepian, American journalist, author, podcaster, and senior investigative producer at Dateline NBC. David Slepian (1923–2007), American mathematician Jan Slepian (1921–2016), author of books for children and young adults Joseph Slepian (1891–1969), American electrical engineer known for his contributions to the developments of electrical apparatus and theory Vladimir Slepian, a.k.a. Eric Pid (1930–1998), French artist and writer of Russian-Jewish origin