Puttrich joined the CDU in 1977. In 1985, she was elected to the Nidda city council, where she served for ten years. During this time, she was also active on the local advisory board for several years. On 22 January 1995, she was elected mayor of Nidda in a
direct election, succeeding Helmut Jung (
SPD). She successfully defended her office in two subsequent direct elections. Puttrich has been a member of the Federal Executive Committee of the CDU's Association of Local Politicians since 1999 and deputy state chairwoman in Hesse. In 2006, she was elected district chairwoman of the CDU Wetterau and a member of the district council. She has been a member of the CDU Hesse Presidium since 2002 and became its deputy state chairwoman in 2010. She also served on the
CDU Federal Executive Committee until 2024. Lucia Puttrich served as President and Vice President of the Hessian Association of Towns and Municipalities from 2001 to 2009, alternating between the two positions. From 2010 to 2014 she was Hessian
Minister for the Environment in the . In the
2013 Hessian state election, she won a seat via a party list position. In the
Second Bouffier cabinet, she was appointed as State Minister for Federal and European Affairs on 18 January 2014. In the
2018 Hessian state election, she won the direct mandate in constituency 26 (Wetterau II constituency) with 29.4 percent of the votes cast. In the
Third Bouffier cabinet, she was reappointed Minister of State for Federal and European Affairs on 18 January 2019. She held this office again in the
First Rhein cabinet from 31 May 2022. With the formation of the
Second Rhein cabinet, she left her ministerial post on 18 January 2024. She did not run again in the
2023 Hessian state election. She thus left the Hessian State Parliament at the inaugural session of the 21st Hessian State Parliament on 18 January 2024. Her successor as constituency representative was (CDU). In 2024 she received the
Hessian Order of Merit. == Bundestag ==