All aerial parts of the tree have stinging hairs, and can cause a severe reaction on contact with skin, so it is a hazard to livestock, travelers and campers. However, the tree is an important member of the ecosystems of eastern Australian forests. The sting is considered more severe than
Dendrocnide photiniphylla (shining-leaved stinging tree), but not as severe as
Dendrocnide moroides (gympie stinger). The tree delivers
neurotoxin proteins which researchers named
gympietides, similar to toxins found in spiders and cone snails, and not previously seen in plants. It was postulated that the long-term pain from the gympietides may be due to permanent changes in the sodium channels in sensory neurons. The venom binds to and fires pain receptors in the nervous system; there are hopes that understanding how these proteins work could lead to the creation of new painkillers. Minor stings can last for an hour or two. However, severe stinging can last for months. First aid for the sting is to apply
wax hair-removal strips and then yank them off to remove the trees' hairs.
Dendrocnide stings have been known to kill dogs and horses that have brushed against them. It was found that even heavy welding gloves did not protect researchers from stings while studying the tree. == Uses ==