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Deoxynucleoside kinase

Deoxynucleoside kinases are generally grouped into two families based on structural homology:

Catalyzed reaction
In enzymology, a deoxynucleoside kinase () is an enzyme that catalyzes the chemical reaction :ATP + 2'-deoxynucleoside \rightleftharpoons ADP + 2'-deoxynucleoside 5'-phosphate Thus, the two substrates of this enzyme are ATP and 2'-deoxynucleoside, whereas its two products are ADP and 2'-deoxynucleoside 5'-phosphate. This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is '''ATP:deoxynucleoside 5'-phosphotransferase. Other names in common use include multispecific deoxynucleoside kinase, ms-dNK, multisubstrate deoxyribonucleoside kinase, multifunctional deoxynucleoside kinase, D. melanogaster deoxynucleoside kinase, and Dm-dNK'''. ==Structural studies==
Structural studies
As of late 2007, 5 structures have been solved for this class of enzymes, with PDB accession codes , , , , and . ==References==
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