Main •
Archie Panjabi as Kendra Malley: the lead Transport Safety and Investigations Bureau (TSIB) investigator •
Kris Holden-Ried as Dominic Hayes: a TSIB investigator •
Mark Rendall as Theo Barker: a TSIB investigator •
Christopher Plummer as Howard Lawson: the senior manager of the TSIB and Kendra's mentor (season 1, recurring role season 2)
Season 1 •
Peter Mensah as Levi Hall: a senior TSIB investigator •
Sasha Roiz as Pavel Bartok:
Russian oligarch and the CEO of Bartok Airways •
Rebecca Liddiard as Madelyn Strong: the sole survivor of British Global Air (BGA) Flight 716 •
Shazad Latif as Ali Basra: Madelyn Strong's boyfriend • Tamara Duarte as Nadia: a TSIB investigator • Alexandre Bourgeois as AJ Malley: Kendra's bitter, criminal, adopted son •
Kristian Bruun as Daniel Hoffman: a passenger on BGA 716 •
Evan Buliung as Derek Strong: Madelyn Strong's father •
Allan Hawco as Richard Donovan: pilot of BGA 716 •
Claire Forlani as Janet Friel: an MI5 officer assigned to the investigation •
Dougray Scott as Ethan Moreau: the CEO of British Global Air
Season 2 •
Karen LeBlanc as Ellen Hunter •
Jason O'Mara as Max O'Neill •
David Hewlett as Bill Ratch • Dion Johnstone as Jordan Cole •
Kelly McCormack as Charlotte • Etienne Kellici as Lucas •
Charlie Carrick as Richard Bright •
Wendy Crewson as Diana Bright •
Donal Logue as Sheriff McCullough • Florence Ordesh as Rose Tate
Season 3 •
Patrick Sabongui as Shakir Urgessa • Savonna Spracklin as Annie Sullivan • Mikaela Dyke as Terry-Lynn Crawford • Brit MacRae as Jessica Hicks • Cihang Ma as Michelle • Tyler Elliott Burke as Arlo Shank •
Eric McCormack as Cole Banks • Pamela Estrada as Lily •
Ben Carlson as Jack Bazin ==Production==