Akhavan made her first short film
Two Drink Minimum while studying in London as a graduate student. Akhavan has regularly appeared in her own work following her writing, directing, and acting in the lesbian-themed
web series The Slope. She and
Ingrid Jungermann, her creative partner, were named to
Filmmakers 25 New Faces of Independent Film in 2012. The series premiered in 2011. In 2014, Akhavan's film
Appropriate Behavior, in which she plays an alternative version of herself, premiered at the
Sundance Film Festival. The film was first written as her senior thesis paper as a graduate student at New York University. In 2015, Akhavan was the President of the Queer Palm jury at the
Cannes Film Festival. She has stated she draws inspiration from people such as
Todd Solondz and
Noah Baumbach. It aired on October 10, 2018, in the U.K. and on November 16, 2018, in the U.S. The sitcom explores misconceptions of bisexuality. In an interview with UK's
Bazaar, she said, "To me that was the perfect way to handle bisexuality, through the lens of a lesbian." The critically acclaimed film won the 2018 Grand Jury Prize at the
Sundance Film Festival, and was officially selected for the 2018
Tribeca Film Festival,
Seattle International Film Festival, Toronto LGBT Film Festival,
San Francisco International LGBTQ Film Festival,
Outfest, and the San Francisco Indie Film Festival, earning multiple additional nominations and awards. In an interview about her career with
The Guardian, Akhavan proclaimed, "The only mainstream queer female stories have been directed by men--it disgusts me." In the same interview, Akhavan explains her intentions behind directing
The Miseducation of Cameron Post. "I didn’t want it to be propaganda, though I think that would be a more commercially successful film. I wanted the tone to be right… Every film about teens is really about the moment they realise that none of the adults know what they’re doing." In 2024, Akhavan's essay collection ''You're Embarrassing Yourself: Stories of Love, Lust and Movies'' was released. It follows Akhavan's life from childhood, to a nose job, to her time as an NYU graduate student, to her success as a filmmaker, all written in her characteristic self-deprecating humour. The book won the award for Bisexual Nonfiction at the
37th Lambda Literary Awards. == Activism ==