The first written reference of the lands that today form part of Desnianskyi District dates back to 1667. Until 1927 the area of the raion belonged to the
Oster uyezd of the
Chernigov Governorate. Since then it became part of the city of Kyiv. In 1932 the area was reorganized under the Petriv (
Podil) Raion. It was not until 1987 when the area was reorganized into a separate raion partially out of the neighboring
Dnipro Raion and was named as the
Vatutin Raion, In October 2001 it was renamed Desnianskyi.
Vyhurivshchyna-Troieshchyna Residential development of what would become known as Troieshchyna microdistrict started in 1966. However it was not until the completion of
Pivnichnyi Bridge (named Moskovskyi Bridge until 2018) in 1976 that the development became genuinely large-scale. ==Population==