There are a lot of
mRNAs that have been
transcribed but not
translated during dictyate. Shortly before ovulation, the oocyte of interest activates these mRNA strains.
Biochemistry mechanism Translation of mRNA in dictyate is partly explained by molecules binding to sites on the mRNA strain, which results in that
initiation factors of translation can not bind to that site. Two such molecules, that impedes initiation factors, are
CPEB and
maskin, which bind to
CPE (cytoplasmic polyadenylation element). When these two molecules remain together, then maskin binds the initiation factor
eIF-4E, and no translation occurs. On the other hand, dissolution of the CPEB/maskin complex leads to eIF-4E binding to the initiation factor
eIF-4G, and thus translation starts, which contributes to the end of dictyate and further maturation of the oocyte. ==See also==