Diego made his on-screen debut in the 2013 telenovela Corazón indomable, portraying the heartwarming character Miguelito at just three years old. His performance won immediate public affection and marked the beginning of a steady acting career. In 2014–2015, he appeared as Mauricio González Sáenz nicknamed “Gansito” in Mi corazón es tuyo, where his portrayal left a memorable impression on viewers Between 2015 and 2018, Diego expanded his television presence with roles in several prominent telenovelas and series like as A que no me dejas, Mujeres de negro, Enamorándome de Ramón and La piloto. In 2020, Escalona appeared in the Telemundo telenovela La doña, portraying Ángel Contreras, the son of the character played by Carlos Ponce. That same year, he participated in the Mexican supernatural horror film La marca del demonio, where he played the role of young Karl Nüni. In 2021, he was cast as Nicolás "Nicky" Torres in the Spanish-language American television series in
Los Angeles La suerte de Loli, a comedy-drama produced by Telemundo. In the series, he worked alongside Silvia Navarro and Osvaldo Benavides. In 2022, Escalona appeared in the Vix+ original series La mujer del diablo, playing the role of Rodrigo. The following year, in 2023, he was cast as Tony Uriarte in the TelevisaUnivision telenovela Golpe de suerte. In 2025, he appeared as Lucas in the reboot of Rosario Tijeras, further solidifying his presence in contemporary Mexican television drama. ==Filmography==