His squad was involved with the kidnapping of a drug lord who in revenge killed every squad member except Murillo, who managed to escape to the city of
Itagüí. In this city he became acquainted with the Galeano family, partners of
Pablo Escobar and members of the
Medellín Cartel. The Galeanos controlled then what was called the
Oficina de Envigado. Murillo became one of the top aides of the family, and it was as such that he received the gun injury that would give him a permanent limp. The Galeanos, however, fell out of favor with Escobar, who ordered them killed in 1992. Murillo managed to survive and then joined
Los Pepes, an organization headed by the Castaño brothers,
Carlos and
Fidel to counter Escobar. He also managed to gain control over the illegal businesses controlled by the Galeanos in Itagüí, including the Oficina de Envigado. Soon, Murillo had become the leader of the many criminal and
hitmen gangs in
Medellín, particularly the fearsome
La Terraza, which was involved in theft, blackmail, extortion, assassination, kidnapping, and drug trafficking. Around the year 2000, however, members of La Terraza rebelled against Murillo and started a war against him. By then, Murillo had become well acquainted with the Castaño brothers and had also become the commander of two paramilitary blocs, the
Cacique Nutibara Bloc and the
Granada Heroes Bloc. He also gained control over much of the drug traffic in the area. He became third in the
chain of command of the
AUC and a key player during the peace process in
Santa Fe de Ralito,
Córdoba between his organization and the government of
Colombia, and he demobilized in November, 2003. However, in 2005 he was accused by a court of being responsible for the death of a deputy. He then escaped from Santa Fe de Ralito and surrendered to authorities four days later. == Extradition to the United States ==