Neu-Ulm was created in 1949, then known as
Dillingen. It acquired its current name in the 1965 election. In the 1949 election, it was Bavaria constituency 43 in the numbering system. In the 1953 through 1961 elections, it was number 238. In the 1965 through 1998 elections, it was number 241. In the 2002 and 2005 elections, it was number 256. In the 2009 through 2021 elections, it was number 255. From the 2025 election, it has been number 254. Originally, the constituency comprised the independent cities of
Neu-Ulm,
Dillingen an der Donau, and
Günzburg and the districts of Landkreis Neu-Ulm, Landkreis Dillingen an der Donau, and Landkreis Günzburg. In the 1965 through 1972 elections, it lost the city and district of Dillingen an der Donau while gaining the districts of Illertissen and Krumbach. In the 1976 through 1990 elections, it comprised the districts of Neu-Ulm and Günzburg. It acquired the northern part of
Unterallgäu district in the 1994 election. Ahead of the 2025 election, the constituency was reduced to Neu-Ulm and Günzburg. ==Members==