Ordinaries •
Giacomo Richardo Vilanova y Meléndez (1914–1953) •
Benjamin Barrera y Reyes, M.I. (1954–1981) •
Marco René Revelo Contreras (1981–1998) •
Romeo Tovar Astorga, O.F.M. (1999–2016) •
Miguel Angel Moran Aquino (2016– )
Auxiliary bishops •
Benjamin Barrera y Reyes, M.J. (1952–1954), appointed Bishop of Santa Ana •
Lorenzo Michele Joseph Graziano, O.F.M. (1961–1965), appointed
Coadjutor Bishop of San Miguel •
Fernando Sáenz Lacalle, O.F.M. (1984–1995), appointed Archbishop of San Salvador •
Luis Morao Andreazza, O.F.M. (2003–2007), appointed Bishop of Chalatenango •
José Elías Rauda Gutiérrez, O.F.M. (2008–2009), appointed Bishop of San Vicente ==Territorial losses==