Several models about the structural hierarchy of distress tolerance have been proposed. Some work suggests that physical and psychological tolerance are distinct constructs. Specifically, sensitivity to feelings of
anxiety and tolerance of negative emotional states may be related to each other as aspects of a larger construct representing sensitivity and tolerance of affect broadly; discomfort surrounding physical stressors, however, was found to be an entirely separate construct not associated with sensitivity to emotional states. Notably, this preliminary work was conducted with self-report measures, and findings are cross-sectional in nature. The authors advise that additional longitudinal work is necessary to corroborate these relationships and elucidate the direction of causality. Recent work extends the distinction between emotional and physical distress tolerance into a higher-order construct, global experiential distress tolerance. This framework draws upon tolerance constructs that have been historically studied as distinct from distress tolerance. The five following constructs are framed as lower-order factors for the global distress tolerance construct, and include: • Tolerance of
uncertainty, or "the tendency to react emotionally, cognitively, or behaviorally to uncertain situations" • Tolerance of
ambiguity, or "the perceived tolerance of complicated, foreign, and/or vague situations of stimuli" • Tolerance of
frustration, or "the perceived capacity to withstand aggravation (e.g., thwarted life goals)" Within models that conceptualize distress tolerance solely as the ability to endure negative emotional states, it is hypothesized to be multidimensional. This includes individual processes related to the anticipation of and experience with negative emotions, such as perceived and actual ability to tolerate the negative emotion, the appraisal of a given situation as acceptable or not, the degree to which an individual can regulate their emotion in the midst of a negative emotional experience, and the amount of attention dedicated to processing the negative emotion. == Biological bases ==