DMT-d4

DMT-d4 is thought to be resistant to metabolism by monoamine oxidase (MAO) compared to DMT. Relatedly, D4DMT, at the same dose, shows stronger effects, 2- to 3-fold higher brain levels, a longer duration, and a faster onset than DMT in rodents. In addition, DMT-d4, unlike DMT, might be orally active, though this remains to be studied. D4DMT was said to have similar properties to the combination of DMT with a monoamine oxidase inhibitor (MAOI) in rodents. The metabolism and metabolites of DMT-d4 have been studied. ==Chemistry==

Synthesis The chemical synthesis of DMT-d4 has been described. Analogues A notable analogue of DMT-d4 is 5-MeO-DMT-d4. Other analogues of DMT-d4 include deuterated forms of tryptamine like α,α-dideuterotryptamine and β,β-dideuterotryptamine. ==History==

DMT-d4 was first described in the scientific literature by 1982. == See also ==