Westbury Clinic • Dr. Clint "Doc" Cassidy (
Billy Ray Cyrus) is a kindhearted doctor from Montana who has moved to New York to work at Westbury Clinic, a medical center adjacent to the local hospital. He initially left Montana to be with his girlfriend Samantha (
Claudette Mink), but he breaks up with her in the pilot because they're from different worlds. Clint has a love for God and for people, making him a popular doctor at the clinic. He often likes to insert some bits of wisdom from Montana into the clinic team's activity. It is mentioned in some episodes that Clint's parents died when he was young; he was taken in by his hometown's doctor, Doc Johansson. This adoption leads to Clint's love for medicine. He is the show's main character. • Nancy Nichol (Andrea C. Robinson) is a young nurse who is smart, energizing, and a bit vain. She possesses good bedside manners, common sense, and a sharp wit. She isn't afraid to speak her mind. Nancy's parents divorced when she was 12, and Nancy had a touching reunion with her mother, who had cancer at the time. This reunion, and the mother eventually succumbing to her cancer, were the focuses of two episodes of the shows. She and Clint have a mutual relationship that is the focus of several episodes. Clint proposes to her in the final episode, and she says "yes". • Dr. Derek Hebert (
Derek McGrath) is a portly, witty, insightful doctor who is a very good friend of Clint's. Derek is friends with the majority of clinical team (except for Dr. Crane) and, despite his soft-spoken personality, never afraid to get involved in anything the clinic is involved in. Derek has a wife, Nellie, and a daughter, Gracie. He fears small rodents, especially rats and mice. • Donna Dewitt (
Ruth Marshall) is the clinic-hospital administrator. She combines a warm heart with a focus on the bottom line. Her occasional role as an antagonist as a result of her goal of cutting costs contrasts with her warmth, approachability and unfailing support of the rest of the staff. • Dr. Oliver Crane (
Ron Lea) is frequently the antagonist of the series. He is egotistical and selfish, and usually more concerned with his individual convenience and getting recognition from peers (especially outside the clinic) than with his patients. He is also a schemer in a sense, trying to get money and compliments, but these almost always fail. But despite his mean, outspoken personality, Oliver did soften slightly toward the end of the show's run. • Tippy Williams, later Tippy Doss (Paula Boudreau), appears in the pilot episode, and joins Westbury later in the first season. She thinks differently than most people, and often comes across as a bit of a dimwit. She keeps the team on their toes in a silly, geeky way, but shining through Tippy's somewhat woolly mind is a heart of gold that loves, sacrifices, and longs to learn.
Jackson Family • Nate Jackson (Richard Leacock) is an officer with the New York Police Department. Nate Jackson is initially skeptical of Clint's country ways, but the two become close friends quickly. Nate is also a building supervisor, and arranges an apartment for Clint. He affectionately gives Clint the nickname "Country". • Raul Garcia (
Tyler Posey) is an orphaned boy who is 8 years old when the series starts and around 11–12 when it ends. He and his single mother were homeless, and they slept in the basement of a New York church before Mrs. Garcia became ill and died. Despite attempts by his abusive father to get custody of Raul, he ends up getting adopted by Nate and Beverly Jackson. Raul is a normal preteen boy who gets instruction on making wise choices from his parents and from Clint, among others. • Beverly Jackson (Tracy Shreve) is Nate's caring, conscientious wife who teaches at Raul's school. She gets pregnant in the first half of season three and gives birth to baby Mattie at the season's end.
Other supporting characters • Justin (
Demetrius Joyette) is Raul's best friend from school. They're good friends who often hang out together. Justin is a bit younger than Raul and sometimes lacks his older friend's good sense. • Elliot (
Taylor Abrahamse) is an aspiring violinist, but somewhat of a nerd. Raul and Justin are reluctant to hang out with him at first, but they soon come to learn that he is a good friend indeed. • Steve "The Captain (later 'Major')" Doss (
Kevin Jubinville) is a soldier in the
U.S. Army who falls in love with Tippy and eventually marries her. He is generally good-natured and very army savvy (he speaks in the manner of a soldier on duty), but he has a tendency to be stiff and formal. • Jelly Bean (Kenny Robinson) and Junior (Billy Otis) are street Peddlers and good friends of Clint's. When they first met they tried to rob Clint but he stopped them and helped them change their ways. • Dr. Harley Johanson (Neil Dainard) Is a mentor and friend to Clint Cassidy. He lives in Montana and is one of Clint's best friends. Clint sees Harley as a father figure. Clint often e-mails Harley at the end of the episode. He appears in 23 episodes.
Notable guest stars • Christian singer
Steven Curtis Chapman appears in the season two episode "Fearless", as Raul's music teacher, Daniel Parson • Cyrus's real-life daughter
Miley Cyrus appears in three episodes; her on-screen acting debut in the Pilot (Part one; uncredited) as Kylie in season two, episode eight (credited as Destiny Hope); and in season four, episode six as Raul's friend; Cyrus's other daughter
Noah Cyrus appears in six episodes as Gracie Hebert •
Michael Cera appears in two season two episodes as Max, a distraught preteen boy whose parents are on the edge of divorce •
Sue Thomas appears in season five, episode seven • Christian singer
Jaci Velasquez appears in the season five episode "Nip, Tuck & Die" • Christian singer
CeCe Winans appears in season three, episode seven as Rosalyn Franklin, a poor Black widow whose young son has leukemia ==Episodes==