Modelling Dominic began modeling and endorsing several companies before heading into acting. He is a model of Cosmopolitan Talent Agency since 2008, and modeled for the Philippine clothing brand,
Penshoppe.
Acting In 2010, Roque debuted onscreen in the soap opera
Habang May Buhay playing Mark. He later took his first major role in the fantasy-drama series,
Aryana in 2012. He played the character Hubert, wherein he co-starred and was paired with
Ella Cruz. While taping the series, he did several guesting roles including
Bandila and in the morning talk show
Kris TV in which he spoke about issues relating to
Kathryn Bernardo. After
Aryana ended in January 2013, he signed his second major role in the noontime drama series
May Isang Pangarap where he played the arrogant Alvin. He was paired with Erin Ocampo, an up-and-coming female actress. On December 25, 2016, Roque starred as Fabian in a
horror-
thriller film entitled
Seklusyon, which was an entry to the
2016 Metro Manila Film Festival. The film received a total of 8 awards; the highest number awarded to a film in the competition. ==Other ventures==