Early career Klose begun his career as an amateur racking a 7–0 record. Prior to joining the
UFC, Klose amassed a record of 7–0–1 in organizations such as
Resurrection Fighting Alliance and World Fighting Federation. Klose signed with the UFC in late 2016. He won the fight by split decision, after dropping his opponent with leg kicks in both the first and second round. Klose faced
David Teymur on December 2, 2017, at
UFC 218. He lost the bout via unanimous decision. Klose faced
Lando Vannata on July 7, 2018, at
UFC 226. He won the fight via unanimous decision. Klose faced
Bobby Green on December 15, 2018, at
UFC on Fox 31 He won the fight by unanimous decision. Klose was expected to face
Beneil Dariush on July 13, 2019, at
UFC Fight Night 155. However, on July 7, Dariush pulled out of the fight with an injury. As a result, UFC officials opted to remove Klose from the card and he is expected to be scheduled for a future event instead. Klose faced
Christos Giagos on August 17, 2019, at
UFC 241. He won the back-and-forth fight via unanimous decision. Klose next faced
Beneil Dariush on March 7, 2020, at
UFC 248, a rescheduling of the bout that was canceled in July 2019. He lost the fight via knockout in the second round. Klose was scheduled to face Jai Herbert on February 20, 2021, at
UFC Fight Night 185. However, Herbert pulled out in the weeks leading up to the event and was replaced by
Luis Peña. However, the bout was cancelled after Klose's corner tested positive for
COVID-19. Klose was expected to face
Jeremy Stephens at
UFC on ESPN 22 on April 17, 2021. However, day of the event, it was announced that the bout was scrapped due to Klose sustaining a spinal injury as a result of being shoved by Stephens at the weigh-ins. Despite the fight not happening, it was reported that Klose would receive his show money and compliance pay. After two-year absence from the octagon, Klose was scheduled to face Nikolas Motta on April 16, 2022, at
UFC on ESPN 34. However, Motta was removed from the event for undisclosed reason and he was replaced by Brandon Jenkins. Klose won the fight via technical knockout in round two after knocking Jenkins down multiple times. This win earned him the
Performance of the Night award. Klose was scheduled to face
Carlos Diego Ferreira on July 30, 2022, at
UFC 277. However, Ferreira was forced out the event due an injury and he was replaced by
Rafa García. Klose won the fight by unanimous decision. Klose was scheduled to face
Mark Madsen on October 29, 2022, at
UFC Fight Night 213. However, Klose pulled out in mid-October due to an
anterior cruciate ligament injury. Klose faced
Joe Solecki on December 2, 2023 at
UFC on ESPN 52. Klose won the fight via knockout in round one after slamming Solecki on his head during an armbar attempt. This fight earned him the
Performance of the Night award. Klose faced
Joaquim Silva on May 3, 2024, at
UFC 301. He won the fight by unanimous decision. Klose faced
Joel Álvarez on December 14, 2024 at
UFC on ESPN 63. He lost the fight by knockout via a flying knee and punches in the first round. Klose faced
Edson Barboza on August 16, 2025 at
UFC 319. He won the fight via unanimous decision.{{Cite web |last=Vreeland |first=Daniel |date=2025-08-16 |title=UFC 319: Drakkar Klose Battles Edson Barboza to Unanimous Decision ==Personal life==