After graduating, Takamine began practicing law in
Honolulu. In 1983, he opened his own law office in
Hilo, Hawaii as his father
Yoshito Takamine resigned after 26 years in the Hawaii House of Representatives. The younger Takamine took his father's seat in 1984. Takamine maintains a house in Laupahoehoe but usually lives in Honolulu with his second wife who is a school official there. He has continued to practice labor law, focusing on workers' compensation cases. On behalf of the ILWU, whose ties to the Takamines go back decades, Takamine has pushed a lumber mill in Ookala, and a wood-burning power plant in
Paauilo. Local residents are against both proposals. Takamine and his father played a key role in the controversial 1980s
Kamehameha Schools (formerly Bishop Estate) decision to buy the Hamakua Sugar Company lands and then plant them in eucalyptus. Since 1984, Takamine served as the State Representative for the
Big Island's 1st District until 2007 when he was elected as the State Senator for District 1. During one campaign he "went to bat" at the century-old local Kalanianaole Elementary and Middle School located on the Hamakua Coast. With the demise of the jobs of the sugar-cane industry, the school had declined when Takamine stepped in and revived interest. His roles in the legislature as a Representative have included serving as Chair of several committees, notably the Finance Committee from 1998-2006. He was deposed from this position on the Finance Committee during pre-2007-session faction fighting in the Democratic caucus. During the 2006 campaign, Takamine had co-hosted an official Akaka campaign rally at the Honokaa ranch of Larry Mehau. Takamine and numerous other Democratic elected officials and candidates were photographed there by Hawaii Free Press photojournalists. In this time, different factions were supporting their respective leaders for chair positions. When his faction failed to seat their leader, he was subsequently stripped of his committee chairmanship. He then ran for the Senate seat being vacated by Sen Lorrane Inouye. Dwight Takamine was elected November 4, 2008, as a candidate for the State Senate District 1 which includes Hilo, Hamakua, and Kamuela. His opponent was Republican Ted Hong, a former member of the University of Hawaiʻi Board of Regents and the former state labor negotiator. Takamine campaigned for President
Barack Obama. ==Personal==